Human RSPO3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RSPO3
Locus ID	84870
Kit Components	GA113727G1, RSPO3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113727G2, RSPO3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113727G3, RSPO3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_032784
Synonyms	CRISTIN1; PWTSR; THSD2
Summary	This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013]

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