Human RTN4IP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RTN4IP1
Locus ID	84816
Kit Components	GA113704G1, RTN4IP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113704G2, RTN4IP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113704G3, RTN4IP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001318746, NM_032730
Synonyms	NIMP; OPA10
Summary	This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, cognitive disability, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

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