Human HRP2 (HDGFRP2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HDGFL2
Locus ID	84717
Kit Components	GA113672G1, HRP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113672G2, HRP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113672G3, HRP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001001520, NM_032631, NM_001348169
Synonyms	HDGF-2; HDGF2; HRP-2
Summary	This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. The protein includes an N-terminal PWWP domain that binds to methyl-lysine-containing histones, with specific binding of this protein to tri-methylated lysines 36 and 79 of histone H3, and di- and tri-methylated lysine 20 of histone H4. The protein functions in LEDGF/p75-independent HIV-1 replication by determining HIV-1 integration site selection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]

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