Human BEX2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BEX2
Locus ID	84707
Kit Components	GA113669G1, BEX2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113669G2, BEX2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113669G3, BEX2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001168399, NM_001168400, NM_001168401, NM_032621
Synonyms	BEX1; DJ79P11.1
Summary	This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

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