Human CREB3L3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CREB3L3
Locus ID	84699
Kit Components	GA113664G1, CREB3L3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113664G2, CREB3L3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113664G3, CREB3L3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001271995, NM_001271996, NM_001271997, NM_032607
Synonyms	CREB-H; CREBH; HYST1481
Summary	This gene encodes a member of the basic-leucine zipper family and the AMP-dependent transcription factor family. The encoded protein is localized to the endoplasmic reticulum and acts as a transcription factor activated by cyclic AMP stimulation. The encoded protein binds the cyclic AMP response element (CRE) and the box-B element and has been linked to acute inflammatory response, hepatocellular carcinoma, triglyceride metabolism, and hepcidin expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

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