Human LOXL3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LOXL3
Locus ID	84695
Kit Components	GA113661G1, LOXL3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113661G2, LOXL3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113661G3, LOXL3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001289164, NM_001289165, NM_032603
Synonyms	LOXL
Summary	This gene encodes a lysyl oxidase, which likely functions as an amine oxidase and plays a role in the formation of crosslinks in collagens and elastin. Deletion of the related gene in mouse causes neonatal mortality with cleft palate, spine deformity, and defects in collagen organization. A mutation in this gene was found in a family with Stickler syndrome. [provided by RefSeq, Sep 2016]

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