Human MYPN activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MYPN
Locus ID	84665
Kit Components	GA113639G1, MYPN gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113639G2, MYPN gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113639G3, MYPN gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001256267, NM_001256268, NM_032578, NR_045662, NR_045663
Synonyms	CMD1DD; CMH22; MYOP; RCM4
Summary	Striated muscle in vertebrates comprises large proteins which must be organized properly to contract efficiently. Z-lines in striated muscle are a sign of this organization, representing the ends of actin thin filaments, titin, nebulin or nebulette and accessory proteins required for structure and function. This gene encodes a protein which interacts with nebulin in skeletal muscle or nebulette in cardiac muscle and alpha-actinin. In addition, this gene product can interact with a protein with the I-band indicating it has a regulatory as well as structural function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

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