Human ZGPAT activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZGPAT
Locus ID	84619
Kit Components	GA113608G1, ZGPAT gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113608G2, ZGPAT gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113608G3, ZGPAT gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001083113, NM_001195653, NM_001195654, NM_032527, NM_181484, NM_181485
Synonyms	GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZIP
Summary	Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.[UniProtKB/Swiss-Prot Function]

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