Human DOT1L activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DOT1L
Locus ID	84444
Kit Components	GA113549G1, DOT1L gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113549G2, DOT1L gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113549G3, DOT1L gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_032482
Synonyms	DOT1; KMT4
Summary	The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011]

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