Human MON1A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MON1A
Locus ID	84315
Kit Components	GA113509G1, MON1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113509G2, MON1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113509G3, MON1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001142501, NM_032355
Synonyms	SAND1
Summary	Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (PubMed:23084991).[UniProtKB/Swiss-Prot Function]

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