Human PGAP4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PGAP4
Locus ID	84302
Kit Components	GA113497G1, PGAP4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113497G2, PGAP4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113497G3, PGAP4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001303107, NM_001303108, NM_032342
Synonyms	C9orf125
Summary	Golgi-resident glycosylphosphatidylinositol (GPI)-N-acetylgalactosamine transferase involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins (PubMed:29374258). Required for the initial step of GPI-GalNAc biosynthesis, transfers GalNAc to GPI in the Golgi after fatty acid remodeling by PGAP2 (PubMed:29374258).[UniProtKB/Swiss-Prot Function]

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