Human Transmembrane Protein 175 (TMEM175) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TMEM175
Locus ID	84286
Kit Components	GA113483G1, Transmembrane Protein 175 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113483G2, Transmembrane Protein 175 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113483G3, Transmembrane Protein 175 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001297423, NM_001297424, NM_001297425, NM_001297426, NM_001297427, NM_001297428, NM_032326
Synonyms	hTMEM175
Summary	Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel.[UniProtKB/Swiss-Prot Function]

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