Human GTF2IRD2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GTF2IRD2
Locus ID	84163
Kit Components	GA113400G1, GTF2IRD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113400G2, GTF2IRD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113400G3, GTF2IRD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001281447, NM_032203, NM_173537, NM_001368300
Synonyms	FP630; GTF2IRD2 alpha; GTF2IRD2A
Summary	This gene is one of several closely related genes on chromosome 7 encoding proteins containing helix-loop-helix motifs. These proteins may function as regulators of transcription. The encoded protein is unique in that its C-terminus is derived from CHARLIE8 transposable element sequence. This gene is located in a region of chromosome 7 that is deleted in Williams-Beuren syndrome, and loss of this locus may contribute to the cognitive phenotypes observed in this disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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