Human CCDC98 (FAM175A) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ABRAXAS1
Locus ID	84142
Kit Components	GA113391G1, CCDC98 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113391G2, CCDC98 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113391G3, CCDC98 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001345962, NM_139076
Synonyms	ABRA1; CCDC98
Summary	This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

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