Human Dysbindin (DTNBP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DTNBP1
Locus ID	84062
Kit Components	GA113346G1, Dysbindin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113346G2, Dysbindin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113346G3, Dysbindin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001271667, NM_001271668, NM_001271669, NM_032122, NM_183040, NM_183041, NR_036448
Synonyms	BLOC1S8; DBND; HPS7; My031; SDY
Summary	This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

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