Human KREMEN1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KREMEN1
Locus ID	83999
Kit Components	GA113335G1, KREMEN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113335G2, KREMEN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113335G3, KREMEN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039570, NM_001039571, NM_032045, NM_153379
Synonyms	KREMEN; KRM1
Summary	This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]

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