Human EIF2A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EIF2A
Locus ID	83939
Kit Components	GA113318G1, EIF2A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113318G2, EIF2A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113318G3, EIF2A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001319043, NM_001319044, NM_001319045, NM_001319046, NM_032025
Synonyms	CDA02; EIF-2A; MST089; MSTP004; MSTP089
Summary	This gene encodes a eukaryotic translation initiation factor that catalyzes the formation of puromycin-sensitive 80 S preinitiation complexes and the poly(U)-directed synthesis of polyphenylalanine at low concentrations of Mg2+. This gene should not be confused with eIF2-alpha (EIF2S1, Gene ID: 1965), the alpha subunit of the eIF2 translation initiation complex. Although both of these proteins function in binding initiator tRNA to the 40 S ribosomal subunit, the encoded protein does so in a codon-dependent manner, whereas eIF2 complex requires GTP. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

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