Human TMTC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TMTC1
Locus ID	83857
Kit Components	GA113278G1, TMTC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113278G2, TMTC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113278G3, TMTC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001193451, NM_031920, NM_175861, NM_001367875
Synonyms	ARG99; OLF; TMTC1A
Summary	Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3.[UniProtKB/Swiss-Prot Function]

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