Human URP2 (FERMT3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FERMT3
Locus ID	83706
Kit Components	GA113243G1, URP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113243G2, URP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113243G3, URP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_031471, NM_178443
Synonyms	KIND3; MIG-2; MIG2B; UNC112C; URP2; URP2SF
Summary	Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010]

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