Human PLVAP activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLVAP
Locus ID	83483
Kit Components	GA113189G1, PLVAP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113189G2, PLVAP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113189G3, PLVAP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_031310
Synonyms	FELS; gp68; PV-1; PV1
Summary	Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development.[UniProtKB/Swiss-Prot Function]

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