Human Rho GTPase activating protein 24 (ARHGAP24) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGAP24
Locus ID	83478
Kit Components	GA113184G1, Rho GTPase activating protein 24 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113184G2, Rho GTPase activating protein 24 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113184G3, Rho GTPase activating protein 24 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001025616, NM_001042669, NM_001287805, NM_031305, NM_001346093
Synonyms	FILGAP; p73; p73RhoGAP; RC-GAP72; RCGAP72
Summary	This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

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