Human Aph 1b (APH1B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	APH1B
Locus ID	83464
Kit Components	GA113180G1, Aph 1b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113180G2, Aph 1b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113180G3, Aph 1b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001145646, NM_031301
Synonyms	APH-1B; PRO1328; PSFL; TAAV688
Summary	This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]

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