Human MAD3 (MXD3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MXD3
Locus ID	83463
Kit Components	GA113179G1, MAD3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113179G2, MAD3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113179G3, MAD3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001142935, NM_031300
Synonyms	BHLHC13; MAD3; MYX
Summary	This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]

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