Human Sprouty 4 (SPRY4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SPRY4
Locus ID	81848
Kit Components	GA113132G1, Sprouty 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113132G2, Sprouty 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113132G3, Sprouty 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001127496, NM_001293289, NM_001293290, NM_030964
Synonyms	HH17
Summary	This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. [provided by RefSeq, Jun 2014]

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