Human PRR7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PRR7
Locus ID	80758
Kit Components	GA112970G1, PRR7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112970G2, PRR7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112970G3, PRR7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001174101, NM_001174102, NM_030567
Synonyms	MGC10772
Summary	Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN (PubMed:27458189). Might play a redundant role in the regulation of T cell receptor signaling (PubMed:21460222). Might promote apoptosis in T cells (PubMed:21460222).[UniProtKB/Swiss-Prot Function]

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