Human PD L2 (PDCD1LG2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PDCD1LG2
Locus ID	80380
Kit Components	GA112945G1, PD L2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112945G2, PD L2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112945G3, PD L2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_025239
Synonyms	B7DC; bA574F11.2; Btdc; CD273; PD-L2; PDCD1L2; PDL2
Summary	Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).[UniProtKB/Swiss-Prot Function]

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