Human PABPC1L activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PABPC1L
Locus ID	80336
Kit Components	GA112933G1, PABPC1L gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112933G2, PABPC1L gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112933G3, PABPC1L gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001124756, NR_134983, NR_134984, NR_134985, NR_134986, NR_134987
Synonyms	C20orf119; dJ1069P2.3; ePAB; PABPC1L1
Summary	This gene belongs to the polyadenylate-binding protein type-1 family of proteins. Members of this family bind to the polyA tails of mRNAs to regulate mRNA stability and translation. The mouse ortholog of this gene is required for female fertility. In human, expression of a functional protein is regulated by alternative splicing. The protein-coding splice variant for this gene is abundantly expressed in human oocytes, while a noncoding splice variant subject to nonsense-mediated decay is the predominant splice variant expressed in somatic tissues. [provided by RefSeq, Aug 2019]

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