Human PUS1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PUS1
Locus ID	80324
Kit Components	GA112924G1, PUS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112924G2, PUS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112924G3, PUS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001002019, NM_001002020, NM_025215
Synonyms	MLASA1
Summary	This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblastic anemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2009]

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