Human VCIP 135 (VCPIP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	VCPIP1
Locus ID	80124
Kit Components	GA112823G1, VCIP 135 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112823G2, VCIP 135 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112823G3, VCIP 135 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_025054
Synonyms	DUBA3; VCIP135
Summary	Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP (By similarity). Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.[UniProtKB/Swiss-Prot Function]

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