Human PIF1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PIF1
Locus ID	80119
Kit Components	GA112821G1, PIF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112821G2, PIF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112821G3, PIF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001286496, NM_001286497, NM_001286499, NM_025049
Synonyms	C15orf20; PIF
Summary	This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus. [provided by RefSeq, Nov 2013]

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