Human TTC26 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TTC26
Locus ID	79989
Kit Components	GA112774G1, TTC26 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112774G2, TTC26 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112774G3, TTC26 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001144920, NM_001144923, NM_001287512, NM_001287513, NM_001318333, NM_001321740, NM_001321741, NM_001321742, NM_024926
Synonyms	dyf-13; DYF13; IFT56
Summary	Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Not required for IFT complex A ciliary localization or function. Essential for maintaining proper microtubule organization within the ciliary axoneme.[UniProtKB/Swiss-Prot Function]

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