Human GPR177 (WLS) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	WLS
Locus ID	79971
Kit Components	GA112764G1, GPR177 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112764G2, GPR177 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112764G3, GPR177 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001002292, NM_001193334, NM_024911
Synonyms	C1orf139; EVI; GPR177; mig-14; MRP
Summary	Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity).[UniProtKB/Swiss-Prot Function]

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