Human PAQR6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PAQR6
Locus ID	79957
Kit Components	GA112755G1, PAQR6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112755G2, PAQR6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112755G3, PAQR6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001272104, NM_001272105, NM_001272106, NM_001272107, NM_001272108, NM_001272109, NM_001272110, NM_001272111, NM_001272112, NM_001272113, NM_024897, NM_198406, NR_073610
Synonyms	PRdelta
Summary	Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432, PubMed:23161870). Seems to act through a G(s) mediated pathway (PubMed:23161870). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). May be involved in regulating rapid P4 signaling in the nervous system (PubMed:23763432). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23763432, PubMed:23161870).[UniProtKB/Swiss-Prot Function]

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