Human CBLL1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CBLL1
Locus ID	79872
Kit Components	GA112694G1, CBLL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112694G2, CBLL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112694G3, CBLL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001284291, NM_024814, NR_024199
Synonyms	HAKAI; RNF188
Summary	This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Aug 2011]

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