Human XLF (NHEJ1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NHEJ1
Locus ID	79840
Kit Components	GA112668G1, XLF gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112668G2, XLF gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112668G3, XLF gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_024782
Synonyms	XLF
Summary	Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq, Jul 2008]

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