Human FBXO31 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FBXO31
Locus ID	79791
Kit Components	GA112628G1, FBXO31 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112628G2, FBXO31 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112628G3, FBXO31 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001282683, NM_024735, NR_024568
Synonyms	FBX14; Fbx31; FBXO14; MRT45; pp2386
Summary	This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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