Human B7H4 (VTCN1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	VTCN1
Locus ID	79679
Kit Components	GA112543G1, B7H4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112543G2, B7H4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112543G3, B7H4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001253849, NM_001253850, NM_024626, NR_045603, NR_045604
Synonyms	B7-H4; B7h.5; B7H4; B7S1; B7X; PRO1291; VCTN1
Summary	This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

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