Human VEPH1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	VEPH1
Locus ID	79674
Kit Components	GA112539G1, VEPH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112539G2, VEPH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112539G3, VEPH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001167911, NM_001167912, NM_001167915, NM_001167916, NM_001167917, NM_024621
Synonyms	MELT; VEPH
Summary	Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling.[UniProtKB/Swiss-Prot Function]

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