Human RIPOR1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RIPOR1
Locus ID	79567
Kit Components	GA112458G1, RIPOR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112458G2, RIPOR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112458G3, RIPOR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001193522, NM_001193523, NM_001193524, NM_024519
Synonyms	FLJ13725; KIAA1930
Summary	Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006). Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006).[UniProtKB/Swiss-Prot Function]

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