Human BRME1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BRME1
Locus ID	79173
Kit Components	GA112402G1, BRME1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112402G2, BRME1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112402G3, BRME1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001345843, NM_001345844, NM_001345846, NM_001345847, NM_001345848, NM_024323
Summary	Meiotic recombination factor component of recombination bridges involved in meiotic double-strand break repair. Modulates the localization of recombinases DMC1:RAD51 to meiotic double-strand break (DSB) sites through the interaction with and stabilization of the BRCA2:HSF2BP complex during meiotic recombination. Indispensable for the DSB repair, homologous synapsis, and crossover formation that are needed for progression past metaphase I, is essential for spermatogenesis and male fertility.[UniProtKB/Swiss-Prot Function]

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