Human MIS12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MIS12
Locus ID	79003
Kit Components	GA112303G1, MIS12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112303G2, MIS12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112303G3, MIS12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001258217, NM_001258218, NM_001258219, NM_001258220, NM_024039
Synonyms	2510025F08Rik; hMis12; KNTC2AP; MTW1
Summary	Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (PubMed:12515822, PubMed:15502821, PubMed:16585270). Essential for proper kinetochore microtubule attachments (PubMed:23891108).[UniProtKB/Swiss-Prot Function]

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