Human BOULE (BOLL) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BOLL
Locus ID	66037
Kit Components	GA112287G1, BOULE gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112287G2, BOULE gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112287G3, BOULE gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001284358, NM_001284361, NM_001284362, NM_033030, NM_197970
Synonyms	BOULE
Summary	This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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