Human GPBP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GPBP1
Locus ID	65056
Kit Components	GA112224G1, GPBP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112224G2, GPBP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112224G3, GPBP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001127235, NM_001127236, NM_001203246, NM_001331037, NM_022913
Synonyms	GPBP; SSH6; VASCULIN
Summary	This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

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