Human RASAL3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RASAL3
Locus ID	64926
Kit Components	GA112198G1, RASAL3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112198G2, RASAL3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112198G3, RASAL3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_022904, NM_001348027, NM_001348028
Synonyms	DKFZp667E013; FLJ00087; FLJ21438
Summary	This gene belongs to the Ras GTPase-activating proteins (RasGAP) family and encodes a protein with pleckstrin homology (PH), C2, and Ras GTPase-activation protein (RasGAP) domains. This protein is localized near or at the plasma membrane when expressed exogenously. Reduced expression of this gene in some cell lines resulted in increased levels of the active form of Ras (Ras-GTP), suggesting that this gene may play a role in negatively regulating the Ras signaling pathway. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017]

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