Human USP46 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	USP46
Locus ID	64854
Kit Components	GA112177G1, USP46 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112177G2, USP46 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112177G3, USP46 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001134223, NM_001286767, NM_001286768, NM_022832
Synonyms	FLJ11850; FLJ12552; FLJ14283; FLJ39393
Summary	Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Jun 2009]

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