Human ZFP106 (ZNF106) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZNF106
Locus ID	64397
Kit Components	GA112057G1, ZFP106 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112057G2, ZFP106 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112057G3, ZFP106 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001284306, NM_001284307, NM_022473, NM_001366844, NM_001366845, NM_001366846
Synonyms	SH3BP3; ZFP106; ZNF474
Summary	RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.[UniProtKB/Swiss-Prot Function]

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