Human HIF3 alpha (HIF3A) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HIF3A
Locus ID	64344
Kit Components	GA112046G1, HIF3 alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112046G2, HIF3 alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112046G3, HIF3 alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_022462, NM_152794, NM_152795, NM_152796
Synonyms	bHLHe17; HIF-3A; HIF3-alpha-1; IPAS; MOP7; PASD7
Summary	The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]

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