Human ABCG8 activation kit by CRISPRa
CAT#: GA112028
ABCG8 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily G member 8
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | ABCG8 |
Locus ID | 64241 |
Kit Components | GA112028G1, ABCG8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112028G2, ABCG8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112028G3, ABCG8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_022437, NM_001357321 |
Synonyms | GBD4; STSL |
Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN420827 | ABCG8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |