Human PDLIM2 activation kit by CRISPRa

CAT#: GA112026

PDLIM2 CRISPRa kit - CRISPR gene activation of human PDZ and LIM domain 2



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CNY 12255.00


货期*
4周

规格
    • 1 kit

Product images

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PDLIM2
Locus ID 64236
Kit Components

GA112026G1, PDLIM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112026G2, PDLIM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112026G3, PDLIM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_021630, NM_176871, NM_198042, NM_001368120
Synonyms MYSTIQUE; SLIM
Summary This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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