Human SMOC2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SMOC2
Locus ID	64094
Kit Components	GA111969G1, SMOC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111969G2, SMOC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111969G3, SMOC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001166412, NM_022138
Synonyms	bA37D8.1; bA270C4A.1; dJ421D16.1; DTDP1; MST117; MSTP117; MSTP140; SMAP2
Summary	This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

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